Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ACKR3 | P25106 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6556105 | 0.83 | KDM4E (0.55) | KDM4ETSHRALOX15TDP1L3MBTL1 | |
| SCHEMBL6555784 | 0.80 | KDM4E (0.58) | KDM4ETSHRALOX15TDP1L3MBTL1 | |
| SCHEMBL6556146 | 0.79 | ALDH1A1 (0.49) | KDM4ETSHRALOX15TDP1L3MBTL1 | |
| SCHEMBL6556030 | 0.79 | L3MBTL1 (0.52) | KDM4ETSHRALOX15TDP1L3MBTL1 | |
| SCHEMBL6556041 | 0.78 | PDE4A (0.47) | KDM4ETSHRALOX15TDP1L3MBTL1 | |
| SCHEMBL6555815 | 0.77 | PPARG (0.44) | KDM4ETSHRALOX15TDP1L3MBTL1 | |
| SCHEMBL6557314 | 0.76 | L3MBTL1 (0.55) | KDM4ETSHRALOX15TDP1L3MBTL1 | |
| SCHEMBL6555770 | 0.75 | KDM4E (0.59) | KDM4ETSHRALOX15TDP1L3MBTL1 | |
| SCHEMBL6555852 | 0.74 | UBE2N (0.48) | KDM4ETSHRPPARGUBE2NNPC1 | |
| SCHEMBL6555825 | 0.73 | PPARA (0.61) | KDM4ETSHRALOX15TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073643-B1 | NEW HETEROCYCLIC COMPOUNDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | REDDYS LAB LTD DR (IN) | 2004-12-29 | — | — | EP | claimed |