Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6556146 | 0.86 | ALDH1A1 (0.49) | MAPTTSHRL3MBTL1KDM4EALOX15 | |
| SCHEMBL6555815 | 0.83 | PPARG (0.44) | MAPTTSHRL3MBTL1KDM4EALOX15 | |
| SCHEMBL6555567 | 0.83 | PPARA (0.60) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL6555852 | 0.80 | UBE2N (0.48) | MAPTTSHRKDM4ENPC1GAA | |
| SCHEMBL6556037 | 0.80 | PPARA (0.51) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL6556035 | 0.78 | KDM4E (0.53) | TSHRL3MBTL1KDM4EALOX15TDP1 | |
| SCHEMBL6556046 | 0.77 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL3956812 | 0.71 | PPARA (0.45) | MAPTTP53L3MBTL1KDM4ENPC1 | |
| SCHEMBL6555825 | 0.70 | PPARA (0.61) | TSHRL3MBTL1KDM4EALOX15TDP1 | |
| SCHEMBL6076735 | 0.70 | PGR (0.54) | PDE4AL3MBTL1KDM4EFFAR1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073643-B1 | NEW HETEROCYCLIC COMPOUNDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | REDDYS LAB LTD DR (IN) | 2004-12-29 | — | — | EP | claimed |