Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10588512 | 0.89 | OPRM1 (0.32) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL3259895 | 0.73 | LMNA (0.38) | LMNA | |
| SCHEMBL4299636 | 0.73 | LMNA (0.38) | LMNA | |
| SCHEMBL9247244 | 0.73 | LMNA (0.38) | LMNA | |
| Hydrochloric Acid SCHEMBL5176768 | 0.70 | FDPS (0.31) | SPHK1LMNA | |
| Oxirane SCHEMBL27844858 | 0.69 | GPR84 (0.45) | SPHK1CYP2D6LMNAGMNNPOLB | |
| Fluoride SCHEMBL27686800 | 0.69 | LMNA (0.52) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL3419500 | 0.68 | GPR84 (0.37) | SPHK1LMNAGPR84FFAR1 | |
| SCHEMBL1628089 | 0.68 | LMNA (0.32) | LMNA | |
| Oxirane SCHEMBL29242261 | 0.67 | GPR84 (0.41) | SPHK1CYP2D6LMNAGMNNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140020-B1 | LARGE MOLECULE DRUG DELIVERY SYSTEM USING AEROSOLIZED MEMBRANE-MIMETIC AMPHIPHILES | GENEREX PHARM INC (CA) | 2004-03-03 | — | — | EP | claimed |