Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 7/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557376 | 0.81 | TDP1 (0.52) | NPC1ALDH1A1HSD17B10TDP1HTR2A | |
| SCHEMBL6557373 | 0.81 | TDP1 (0.52) | NPC1ALDH1A1HSD17B10TDP1HTR2A | |
| Piperazine SCHEMBL6559517 | 0.71 | ALDH1A1 (0.41) | ALDH1A1HSD17B10TDP1HTR2AKCNH2 | |
| SCHEMBL28814169 | 0.70 | ALDH1A1 (0.44) | ALDH1A1HSD17B10TDP1HTR2AKCNH2 | |
| SCHEMBL21959668 | 0.69 | APP (0.58) | ALDH1A1TDP1APPPTGS2MAPK1 | |
| SCHEMBL28814657 | 0.69 | ALDH1A1 (0.40) | ALDH1A1HSD17B10TDP1HTR2AKCNH2 | |
| SCHEMBL1373939 | 0.69 | HCAR2 (0.57) | NPC1GAAALDH1A1HSD17B10TDP1 | |
| SCHEMBL1375276 | 0.69 | HCAR2 (0.57) | NPC1GAAALDH1A1HSD17B10TDP1 | |
| SCHEMBL9681048 | 0.69 | PTPN1 (0.47) | PTGS2PTGS1CYP3A4MAOBSMN1; SMN2 | |
| SCHEMBL9681054 | 0.69 | PTPN1 (0.47) | PTGS2PTGS1CYP3A4MAOBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916394-B1 | Method of manufacturing modified particles and manufacturing device therefor | SHARP KK (JP) | 2004-03-10 | — | — | EP | disclosed |
| US-6194487-B1 | EXPOSURE OF PARTICLES TO SUPERSATURATED VAPOR OF MONOMERS, CONDENSATION AND POLYMERIZATION ON THE SURFACE | SHARP KABUSHIKI KAISHA (JP) | 2001-02-27 | — | — | US | disclosed |
| EP-0916394-A2 | Method of manufacturing modified particles and manufacturing device therefor | Sharp Kabushiki Kaisha (JP) | 1999-05-19 | — | — | EP | disclosed |