Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557413 | 0.89 | EGFR (0.37) | TSHRSMN1; SMN2KMT2AKCNA5HTT | |
| SCHEMBL6557230 | 0.80 | SMN1; SMN2 (0.39) | TSHRSMN1; SMN2KMT2AHTTROCK2 | |
| SCHEMBL6557549 | 0.80 | HTT (0.46) | TSHRSMN1; SMN2KMT2AHTTROCK2 | |
| SCHEMBL13091290 | 0.75 | TSHR (0.41) | TSHRSMN1; SMN2KMT2AKCNA5 | |
| SCHEMBL10202757 | 0.73 | HPGD (0.45) | TSHRSMN1; SMN2 | |
| SCHEMBL13104120 | 0.72 | ALDH1A1 (0.39) | TSHRSMN1; SMN2KCNA5 | |
| SCHEMBL6559693 | 0.72 | TSHR (0.43) | TSHRSMN1; SMN2KMT2A | |
| SCHEMBL14162672 | 0.71 | TSHR (0.49) | TSHRSMN1; SMN2 | |
| SCHEMBL1476698 | 0.70 | GABRA1 (0.42) | TSHRSMN1; SMN2HTT | |
| SCHEMBL1476738 | 0.69 | GABRA1 (0.41) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1085010-B1 | PHENYLACETYLENE DERIVATIVES AND AGRICULTURAL/HORTICULTURAL BACTERICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2004-03-10 | — | — | EP | disclosed |
| US-6313071-B1 | Phenylacetylene derivatives and agricultural/horticultural fungicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-1085010-A1 | PHENYLACETYLENE DERIVATIVES AND AGRICULTURAL/HORTICULTURAL BACTERICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-03-21 | — | — | EP | disclosed |