SCHEMBL6558385

SCHEMBL6558385

CCc1n[nH]c(NC(c2ccccc2)(c2ccccc2)c2ccccc2)c1CN

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 2/20 0.38
KIF11 P52732 3/20 0.36
PRMT5 O14744 2/20 0.33
TAAR1 Q96RJ0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6558942 0.89 KCNN4 (0.39) KCNN4KIF11PRMT5TAAR1
SCHEMBL6557082 0.75 PRMT5 (0.40) PRMT5
SCHEMBL6557418 0.69 HSD17B10 (0.36) KCNN4
SCHEMBL6558343 0.68 NPC1 (0.41)
SCHEMBL6558372 0.66 POLB (0.43)
SCHEMBL6559436 0.66 MAPK1 (0.32)
SCHEMBL6559547 0.65 MEN1 (0.34)
SCHEMBL6559480 0.64 KCNN4 (0.34) KCNN4
Ethylamine SCHEMBL28256368 0.63 KCNN4 (0.58) KCNN4KIF11TAAR1
SCHEMBL6065016 0.62 KMT2A (0.33) KCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1392704-A1 CEPHEM COMPOUNDS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-03 EP disclosed
WO-2002090364-A1 CEPHEM COMPOUNDS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-11-14 WO disclosed