Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | AKT2 | P31751 | 1/20 | 0.32 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | VNN1 | O95497 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GCK | P35557 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6065740 | 0.74 | F2 (0.41) | KMT2AMAPTMEN1LMNARAB9A | |
| SCHEMBL6066190 | 0.73 | SMN1; SMN2 (0.35) | KMT2AMAPTFTOLMNAVNN1 | |
| SCHEMBL6558343 | 0.72 | NPC1 (0.41) | KMT2AMAPTP2RX7MEN1LMNA | |
| SCHEMBL6557067 | 0.72 | P2RX3 (0.35) | KMT2AMAPTENPP3ALPLXIAP | |
| SCHEMBL6065131 | 0.71 | LMNA (0.40) | LMNARAB9ASMN1; SMN2 | |
| SCHEMBL6558372 | 0.70 | POLB (0.43) | KMT2AMAPTMEN1LMNAMAPK1 | |
| SCHEMBL6557414 | 0.70 | MTNR1A (0.40) | KMT2AMAPTP2RX7MEN1RAB9A | |
| SCHEMBL6065097 | 0.70 | PKM (0.45) | KMT2AMAPTMEN1LMNAPKM | |
| SCHEMBL6557418 | 0.68 | HSD17B10 (0.36) | KMT2AMAPTKCNN4MEN1LMNA | |
| SCHEMBL6065771 | 0.66 | LMNA (0.35) | FTOLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663245-A1 | CEPHEM COMPOUNDS | Astellas Pharma Inc. (JP) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005027909-A1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2005-03-31 | — | — | WO | disclosed |