Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 2/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558343 | 0.87 | NPC1 (0.41) | TP53MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL6557414 | 0.80 | MTNR1A (0.40) | HPGDTP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6065097 | 0.80 | PKM (0.45) | HPGDMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL6557418 | 0.79 | HSD17B10 (0.36) | POLBHPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6559436 | 0.75 | MAPK1 (0.32) | HPGDMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL6559547 | 0.74 | MEN1 (0.34) | HPGDMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL508530 | 0.72 | PDE4D (0.53) | HPGDMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL6065016 | 0.70 | KMT2A (0.33) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL5147593 | 0.70 | CYP4F2 (0.48) | POLBMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL6065131 | 0.69 | LMNA (0.40) | HPGDSMN1; SMN2LMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392704-A1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002090364-A1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |