Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 3/20 | 0.34 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558385 | 0.89 | KCNN4 (0.38) | KCNN4KIF11PRMT5TAAR1 | |
| SCHEMBL6557418 | 0.70 | HSD17B10 (0.36) | KCNN4KMT2AHPGDLMNAHSD17B10 | |
| SCHEMBL6558343 | 0.68 | NPC1 (0.41) | KMT2ALMNAHSD17B10NPC1MAPT | |
| SCHEMBL6558372 | 0.67 | POLB (0.43) | KMT2AHPGDLMNAHSD17B10MAPT | |
| SCHEMBL6559436 | 0.67 | MAPK1 (0.32) | KMT2AHPGDLMNAHSD17B10MAPT | |
| SCHEMBL6559547 | 0.66 | MEN1 (0.34) | KMT2AHPGDLMNAHSD17B10MAPT | |
| SCHEMBL6557082 | 0.65 | PRMT5 (0.40) | KMT2ALMNAHSD17B10GFERPRMT5 | |
| SCHEMBL6557414 | 0.64 | MTNR1A (0.40) | KMT2AHPGDHSD17B10NPC1MAPT | |
| SCHEMBL28794329 | 0.63 | KCNN4 (0.37) | KCNN4KMT2AHPGDLMNAHSD17B10 | |
| SCHEMBL6558387 | 0.63 | KIF11 (0.38) | KCNN4KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392704-A1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002090364-A1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |