Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559436 | 0.94 | MAPK1 (0.32) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL6557418 | 0.81 | HSD17B10 (0.36) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL6558343 | 0.79 | NPC1 (0.41) | MEN1KMT2AALDH1A1HSD17B10MAPT | |
| SCHEMBL6557414 | 0.77 | MTNR1A (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL6558372 | 0.74 | POLB (0.43) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL6557056 | 0.69 | ADH1B (0.37) | MAPK1DRD4 | |
| SCHEMBL6559480 | 0.69 | KCNN4 (0.34) | — | |
| SCHEMBL5148585 | 0.68 | MEN1 (0.38) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6557067 | 0.67 | P2RX3 (0.35) | KMT2AALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL6558942 | 0.66 | KCNN4 (0.39) | KMT2AALDH1A1HSD17B10MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392704-A1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002090364-A1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |