SCHEMBL6558669

SCHEMBL6558669

CCS(=O)(=O)NC1Cc2cc(C)c(C)cc2OC1(C)C

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
PTPN1 P18031 1/20 0.33
ACHE P22303 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
AR P10275 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6559958 0.86 MGAM (0.34) MGAMGAASIPTPN1ACHE
SCHEMBL7536992 0.80 KCNE1 (0.43)
SCHEMBL6561204 0.78 HIF1A (0.44) ACHE
SCHEMBL6560820 0.69 KCNA5 (0.36)
SCHEMBL6558641 0.59 TRPV1 (0.39)
SCHEMBL6561118 0.58 KDM4E (0.41) MGAMGAASIPTPN1ACHE
SCHEMBL6558621 0.57 TRPV1 (0.37)
SCHEMBL6559509 0.56 TRPV1 (0.45)
SCHEMBL6559538 0.56 TRPV1 (0.37)
SCHEMBL17761372 0.54 TDP1 (0.33) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0807629-B1 Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them AVENTIS PHARMA GMBH (DE) 2004-03-03 EP disclosed
US-6191164-B1 POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 2001-02-20 US disclosed
EP-0807629-A1 Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them HOECHST AKTIENGESELLSCHAFT (DE) 1997-11-19 EP disclosed