Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9692443 | 0.74 | KDM4E (0.44) | KDM4EALDH1A1HPGD | |
| SCHEMBL7659637 | 0.72 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDAVPR1A | |
| SCHEMBL8069814 | 0.72 | KDM4E (0.37) | KDM4EALDH1A1HPGDGAA | |
| SCHEMBL8645380 | 0.70 | KDM4E (0.41) | KDM4EALDH1A1HPGD | |
| SCHEMBL8794691 | 0.70 | TDP2 (0.46) | KDM4EALDH1A1HPGD | |
| SCHEMBL28830167 | 0.70 | MAPT (0.47) | KDM4EALDH1A1HPGDGAA | |
| SCHEMBL8436289 | 0.68 | KDM4E (0.40) | KDM4EALDH1A1HPGD | |
| SCHEMBL6559528 | 0.68 | CA2 (0.43) | KDM4EALDH1A1HPGDHTTGAA | |
| SCHEMBL27671997 | 0.68 | ALDH2 (0.40) | ALDH1A1 | |
| SCHEMBL10293214 | 0.66 | MAOA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807629-B1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |