Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 15/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559589 | 0.80 | TRPV1 (0.52) | TRPV1CFTR | |
| SCHEMBL23423012 | 0.78 | TRPV1 (0.46) | TRPV1CFTR | |
| SCHEMBL6558692 | 0.76 | TRPV1 (0.40) | TRPV1CFTR | |
| Hydrochloric Acid SCHEMBL7830696 | 0.75 | TRPV1 (0.40) | TRPV1CFTR | |
| SCHEMBL6561166 | 0.74 | KCNE1 (0.44) | TRPV1HTR6 | |
| SCHEMBL6559479 | 0.74 | ALDH1A1 (0.35) | — | |
| SCHEMBL6560820 | 0.73 | KCNA5 (0.36) | TRPV1CFTR | |
| SCHEMBL6559509 | 0.72 | TRPV1 (0.45) | TRPV1 | |
| SCHEMBL6558621 | 0.72 | TRPV1 (0.37) | TRPV1CYP11B1CYP11B2 | |
| SCHEMBL6559484 | 0.71 | MAPT (0.36) | TRPV1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807629-B1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |