Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 5/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559444 | 0.78 | KDM4E (0.48) | KDM4ELMNANPSR1GFERALDH1A1 | |
| SCHEMBL6557080 | 0.76 | AGTR1 (0.39) | KDM4ELMNANPSR1GFERALDH1A1 | |
| SCHEMBL6007089 | 0.71 | KDM4E (0.46) | KDM4ELMNANPSR1GFERALDH1A1 | |
| SCHEMBL6004882 | 0.71 | KDM4E (0.46) | KDM4ELMNANPSR1GFERALDH1A1 | |
| SCHEMBL27282842 | 0.69 | MAPKAPK2 (0.46) | KDM4ELMNAMAPKAPK2CACNA1HCACNA1B | |
| SCHEMBL5499877 | 0.69 | NPSR1 (0.39) | KDM4ELMNANPSR1GFERALDH1A1 | |
| SCHEMBL22535990 | 0.69 | TDP1 (0.44) | KDM4ELMNAGFERL3MBTL1HTT | |
| SCHEMBL22198948 | 0.68 | KDM4E (0.48) | KDM4ELMNANPSR1GFERALDH1A1 | |
| SCHEMBL22535987 | 0.67 | TDP1 (0.46) | KDM4ELMNANPSR1GFERL3MBTL1 | |
| SCHEMBL24376424 | 0.67 | GRM2 (0.52) | KDM4ELMNANPSR1GFERPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392704-A1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002090364-A1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |