Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557082 | 0.92 | PRMT5 (0.40) | AGTR1AGTR2PRMT5WDR77CYP1A2 | |
| SCHEMBL6559033 | 0.83 | KDM4E (0.40) | PRMT5WDR77CYP1A2PARP1KDM4E | |
| SCHEMBL6558971 | 0.76 | KDM4E (0.44) | AGTR1AGTR2PRMT5WDR77CYP1A2 | |
| SCHEMBL6558942 | 0.76 | KCNN4 (0.39) | PRMT5KDM4ELMNAGFERHSD17B10 | |
| SCHEMBL5497821 | 0.74 | SIGMAR1 (0.38) | KDM4EGFERL3MBTL1NPSR1BCHE | |
| SCHEMBL6385861 | 0.71 | BCHE (0.40) | CYP1A2GFERNPSR1BCHESIGMAR1 | |
| SCHEMBL6557087 | 0.71 | SIGMAR1 (0.42) | NPSR1BCHESIGMAR1 | |
| SCHEMBL6559029 | 0.70 | SIGMAR1 (0.37) | CYP1A2KDM4ABCHESYKSIGMAR1 | |
| SCHEMBL6557081 | 0.70 | NPSR1 (0.43) | L3MBTL1NPSR1BCHESIGMAR1 | |
| SCHEMBL6557414 | 0.70 | MTNR1A (0.40) | CYP1A2HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392704-A1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002090364-A1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |