Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | RARB | P10826 | 7/20 | 0.39 |
| ▸ | RARG | P13631 | 7/20 | 0.39 |
| ▸ | RARA | P10276 | 6/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.36 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561155 | 0.85 | RAB9A (0.43) | MEN1KMT2AALDH1A1RARBRARG | |
| SCHEMBL3456479 | 0.84 | MEN1 (0.51) | RXRAMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL7479500 | 0.77 | HTR2C (0.42) | MEN1KMT2ATDP1AKR1B1 | |
| SCHEMBL6560005 | 0.77 | KCNE1 (0.43) | RXRAMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL6024993 | 0.76 | CNR1 (0.48) | KDM1AMAPT | |
| SCHEMBL3322619 | 0.76 | TRPV1 (0.41) | KDM1AAKR1B1 | |
| SCHEMBL6024969 | 0.76 | BACE1 (0.37) | ALDH1A1KDM1AAKR1B1 | |
| SCHEMBL6025054 | 0.76 | BACE1 (0.37) | ALDH1A1KDM1AAKR1B1 | |
| SCHEMBL6024931 | 0.76 | TRPV1 (0.41) | KDM1AAKR1B1 | |
| SCHEMBL3409160 | 0.76 | CNR1 (0.48) | KDM1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807629-B1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |