Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559253 | 0.85 | RXRA (0.41) | ALOX5MAPTALDH1A1RARBRARG | |
| SCHEMBL6559262 | 0.79 | TRPV1 (0.43) | RAB9ASMN1; SMN2NPC1ALOX5MAPT | |
| SCHEMBL6559931 | 0.77 | KCNA5 (0.44) | RAB9ASMN1; SMN2NPC1ALOX5MAPT | |
| SCHEMBL6559277 | 0.77 | KCNE1 (0.40) | RAB9ASMN1; SMN2NPC1ALOX5MAPT | |
| SCHEMBL484620 | 0.77 | CYP3A4 (0.45) | RAB9ASMN1; SMN2NPC1MAPTKDM4E | |
| SCHEMBL6558679 | 0.77 | HPGD (0.41) | RAB9ASMN1; SMN2NPC1ALOX5KDM4E | |
| SCHEMBL6559569 | 0.77 | RAB9A (0.37) | RAB9ASMN1; SMN2NPC1ALOX5MAPT | |
| SCHEMBL6561146 | 0.77 | KCNA5 (0.41) | RAB9ASMN1; SMN2NPC1ALOX5MAPT | |
| SCHEMBL3589162 | 0.76 | HTR2B (0.46) | SMN1; SMN2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL6559205 | 0.76 | SMN1; SMN2 (0.38) | RAB9ASMN1; SMN2NPC1ALOX5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807629-B1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |