Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.54 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.54 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.54 |
| ▸ | ABAT | P80404 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.54 |
| ▸ | FDPS | P14324 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23201069 | 0.83 | ALDH1A1 (0.59) | ALDH1A1TSHRHPGDAOX1TRIM24 | |
| SCHEMBL3229664 | 0.80 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGDAOX1TRIM24 | |
| SCHEMBL6542213 | 0.79 | ALDH1A1 (0.54) | ALDH1A1TSHRHPGDAOX1TRIM24 | |
| SCHEMBL29482639 | 0.77 | TRPV4 (0.68) | TRPV4ALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL74997 | 0.77 | TRPV4 (0.68) | TRPV4ALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL2947794 | 0.77 | TRPV4 (1.00) | TRPV4ALDH1A1TSHRHPGDPOLB | |
| SCHEMBL533956 | 0.77 | TRPV4 (0.68) | TRPV4ALDH1A1TSHRPOLBMEN1 | |
| SCHEMBL29420268 | 0.77 | TRPV4 (1.00) | TRPV4ALDH1A1TSHRHPGDPOLB | |
| 3,4-Dimethoxybenzaldehyde SCHEMBL5308959 | 0.75 | ALDH1A1 (1.00) | ALDH1A1TSHRHPGDAOX1TRIM24 | |
| 3,4-Dimethoxybenzaldehyde SCHEMBL1330962 | 0.75 | ALDH1A1 (1.00) | ALDH1A1TSHRHPGDAOX1TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202960-B1 | METHOD FOR THE PREPARATION OF 2-METHOXY-4-(N-T-BUTYLAMINO-CARBONYL)-BENZENESULFONYL CHLORIDE | SANOFI SYNTHELABO (FR) | 2004-03-10 | — | — | EP | claimed |
| EP-1202960-B1 | METHOD FOR THE PREPARATION OF 2-METHOXY-4-(N-T-BUTYLAMINO-CARBONYL)-BENZENESULFONYL CHLORIDE | SANOFI SYNTHELABO (FR) | 2004-03-10 | — | — | EP | disclosed |
| US-6548702-B1 | Sulfonating m-hydroxybenzoic acid; methylation, salt formation, chlorination, reaction with t-butylamine | SANOFI-SYNTHELABO (FR) | 2003-04-15 | — | — | US | disclosed |
| EP-1202960-A1 | METHOD FOR THE PREPARATION OF 2-METHOXY-4-(N-T-BUTYLAMINO-CARBONYL)-BENZENESULFONYL CHLORIDE | SANOFI-SYNTHELABO (FR) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001005754-A1 | METHOD FOR THE PREPARATION OF 2-METHOXY-4-(N-T-BUTYLAMINO-CARBONYL)-BENZENESULFONYL CHLORIDE | SANOFI-SYNTHELABO (FR) | 2001-01-25 | — | — | WO | disclosed |