Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 5/20 | 0.32 |
| ▸ | KCNQ1 | P51787 | 5/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559544 | 0.77 | KCNA5 (0.36) | KCNA5ALDH1A1PKMHTTRECQL | |
| SCHEMBL6560836 | 0.69 | KCNA5 (0.34) | KCNA5ALDH1A1PKMHTTRECQL | |
| SCHEMBL6559403 | 0.68 | KCNA5 (0.37) | KCNA5ALDH1A1PKMHTTRECQL | |
| SCHEMBL6559500 | 0.64 | NPSR1 (0.38) | TDP1KCNA5SMN1; SMN2NPSR1KCNE1 | |
| SCHEMBL6559927 | 0.61 | KCNA5 (0.41) | KCNA5ALDH1A1KCNE1KCNQ1 | |
| SCHEMBL10822265 | 0.61 | RXRA (0.48) | TDP1RXRAALDH1A1SMN1; SMN2 | |
| SCHEMBL6558561 | 0.61 | KCNE1 (0.34) | KCNA5NPSR1KCNE1KCNQ1 | |
| SCHEMBL6558501 | 0.61 | KCNE1 (0.45) | RXRAKCNA5KCNE1KCNQ1 | |
| SCHEMBL30195971 | 0.61 | RXRA (0.64) | TDP1RXRAALDH1A1PKM | |
| SCHEMBL3880185 | 0.61 | RXRA (0.64) | TDP1RXRAALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807629-B1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |