Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559992 | 0.90 | PLAU (0.50) | PLAUSGMS2NPC1PKMRAB9A | |
| SCHEMBL7604271 | 0.89 | NPC1 (0.52) | PLAUSGMS2NPC1PKMRAB9A | |
| SCHEMBL14524175 | 0.84 | SGMS2 (0.49) | PLAUSGMS2NPC1PKMRAB9A | |
| SCHEMBL6560278 | 0.82 | POLB (0.57) | SGMS2 | |
| SCHEMBL17864888 | 0.80 | LMNA (0.61) | PLAUPKMMAPTL3MBTL1LMNA | |
| SCHEMBL17008889 | 0.79 | PLAU (0.49) | PLAUMAPTL3MBTL1LMNASMN1; SMN2 | |
| Benzyl Benzylcarbamate SCHEMBL1136818 | 0.79 | PLAU (0.70) | PLAULMNASMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL28877556 | 0.78 | FOLH1 (0.57) | FOLH1MCL1L3MBTL1 | |
| Benzyl Benzylcarbamate SCHEMBL9998166 | 0.77 | PLAU (0.68) | PLAULMNASMN1; SMN2HDAC3HDAC1 | |
| Benzyl Benzylcarbamate SCHEMBL19810513 | 0.77 | PLAU (0.68) | PLAULMNASMN1; SMN2HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208322-B2 | Sensor surfaces for detecting analytes | AGILENT TECHNOLOGIES, INC. (US) | 2007-04-24 | — | — | US | disclosed |
| US-7208322-B2 | Sensor surfaces for detecting analytes | AGILENT TECHNOLOGIES, INC. (US) | 2007-04-24 | — | — | US | disclosed |
| US-7179659-B2 | Detection of preferential particles in sample; obtain sample, incubate with sensor and substrate, monitor and measure response, evaluate for presence of particle | AGILENT TECHNOLOGIES, INC. (US) | 2007-02-20 | — | — | US | disclosed |
| US-7179659-B2 | Detection of preferential particles in sample; obtain sample, incubate with sensor and substrate, monitor and measure response, evaluate for presence of particle | AGILENT TECHNOLOGIES, INC. (US) | 2007-02-20 | — | — | US | disclosed |
| EP-1391454-A1 | Substituted benzamide compounds with antihypertensive activity | Mitsubishi Pharma Corporation (JP) | 2004-02-25 | — | — | EP | disclosed |
| EP-0920413-B1 | BORONIC COMPOUND COMPLEXING REAGENTS AND COMPLEXES | PROLINX INC (US) | 2002-11-13 | — | — | EP | disclosed |
| EP-1195372-A1 | N-heterocyclic substituted benzamide derivatives with antihypertensive activity | Mitsubishi Pharma Corporation (JP) | 2002-04-10 | — | — | EP | disclosed |
| US-6156766-A | Benzamide compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2000-12-05 | — | — | US | disclosed |
| US-5958944-A | TREATMENT OF CIRCULATORY DISEASES IN CORONARY, CEREBRAL, RENAL AND PERIPHERAL ARTERIES, AS A THERAPEUTIC AGENT FOR HYPERTENSION, ANGINA PECTORIS, AND RENAL AND PERIPHERAL CIRCULATION DISORDER, ANTIASTHMATIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-28 | — | — | US | disclosed |
| EP-0920413-A1 | BORONIC COMPOUND COMPLEXING REAGENTS AND COMPLEXES | PROLINX, INC. (US) | 1999-06-09 | — | — | EP | disclosed |
| US-5877297-A | Boronic compound complexing reagents and highly stable complexes | PROLINX, INC. (US) | 1999-03-02 | — | — | US | disclosed |
| US-5872224-A | Boronic compound complexing reagents and highly stable complexes | PROLINX, INC. (US) | 1999-02-16 | — | — | US | disclosed |
| US-5869623-A | Boronic compound complexing reagents and complexes | SYSTEMIX (US) | 1999-02-09 | — | — | US | disclosed |
| US-5859210-A | Boronic compound complexing reagents and complexes | PROLINX, INC. (US) | 1999-01-12 | — | — | US | disclosed |
| US-5847192-A | Boronic compound complexing reagents and complexes | PROLINX, INC. (US) | 1998-12-08 | — | — | US | disclosed |
| US-5837878-A | Boronic compound complexing reagents and highly stable complexes | PROLINX, INC. (US) | 1998-11-17 | — | — | US | disclosed |
| US-5777148-A | Boronic compound complexing reagents and highly stable complexes | PROLINX, INC. (US) | 1998-07-07 | — | — | US | disclosed |
| US-5744627-A | Boronic compound complexing reagents and complexes | PROLINX, INC. (US) | 1998-04-28 | — | — | US | disclosed |
| WO-1998005629-A1 | BORONIC COMPOUND COMPLEXING REAGENTS AND COMPLEXES | PROLINX, INC. (US) | 1998-02-12 | — | — | WO | disclosed |
| EP-0757038-A1 | BENZAMIDE COMPOUND AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-02-05 | — | — | EP | disclosed |