Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 5/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561204 | 0.88 | HIF1A (0.44) | HIF1ACA2ACHECA1ABCB1 | |
| SCHEMBL11386682 | 0.74 | HIF1A (0.52) | HIF1ACA2MTNR1AMTNR1BCA5A | |
| SCHEMBL6592058 | 0.70 | HIF1A (0.50) | HIF1A | |
| SCHEMBL6594263 | 0.70 | CA1 (0.48) | HIF1ACA2CA1 | |
| SCHEMBL224104 | 0.69 | HIF1A (0.45) | HIF1AABCB1HTR2CDRD2DRD3 | |
| SCHEMBL225757 | 0.68 | HIF1A (0.44) | HIF1ADRD3 | |
| SCHEMBL14327006 | 0.67 | HIF1A (0.46) | HIF1AACHE | |
| SCHEMBL16109188 | 0.67 | CA2 (0.44) | HIF1ACA2CA5AHTR2CDRD2 | |
| SCHEMBL16745489 | 0.66 | DRD2 (0.40) | HIF1ACA2ACHEMTNR1ACA5A | |
| SCHEMBL11295099 | 0.66 | MTNR1A (0.55) | CA2ACHECA1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807629-B1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |