SCHEMBL6560154

SCHEMBL6560154

C=CC(=O)OC12CC3CC(C1)CC(C(=O)OC)(C3)C2

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.39
NPSR1 Q6W5P4 1/20 0.37
THRB P10828 1/20 0.34
ALDH1A1 P00352 3/20 0.33
TSHR P16473 2/20 0.33
ABL1 P00519 1/20 0.33
RIN1 Q13671 1/20 0.33
LMNA P02545 1/20 0.33
NAAA Q02083 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
SCN1A P35498 1/20 0.32
SCN2A Q99250 1/20 0.32
SCN3A Q9NY46 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14593987 0.88 NPSR1 (0.35) GLANPSR1ALDH1A1LMNAMEN1
SCHEMBL14593991 0.86 SCN1A (0.35) GLANPSR1ALDH1A1LMNAMEN1
SCHEMBL6561662 0.85 GLA (0.34) GLANPSR1THRBALDH1A1LMNA
SCHEMBL1733328 0.85 CYP17A1 (0.35) GLANPSR1MEN1KMT2ASCN1A
SCHEMBL14594000 0.84 PKM (0.38) NPSR1ALDH1A1KMT2ASCN1ASCN2A
SCHEMBL3953932 0.84 PKM (0.41) GLANPSR1THRBALDH1A1LMNA
SCHEMBL822780 0.83 ALDH1A1 (0.36) GLANPSR1THRBALDH1A1TSHR
SCHEMBL5608715 0.82 THRB (0.42) GLANPSR1THRBALDH1A1TSHR
SCHEMBL15100557 0.82 GLA (0.31) GLA
SCHEMBL5607848 0.82 NPSR1 (0.40) GLANPSR1THRBALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0915077-B1 POLYMERIZABLE ADAMANTANE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME DAICEL CHEM (JP) 2004-11-17 EP disclosed
US-6235851-B1 ESTERIFICATION OR AMIDATION REACTION OF AN ADAMANTANE DERIVATIVE; GROUP 3A METAL CATALYST DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2001-05-22 US disclosed
EP-0915077-A1 POLYMERIZABLE ADAMANTANE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME Daicel Chemical Industries, Ltd. (JP) 1999-05-12 EP disclosed