SCHEMBL6560253

SCHEMBL6560253

CCc1nc([Se]c2cc3c(cc2OCOC(C)OC)C(C)(C)CCC3(C)C)ccc1C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
RXRA P19793 16/20 0.37
HNF4A P41235 5/20 0.37
RXRB P28702 4/20 0.35
RXRG P48443 4/20 0.35
RARG P13631 4/20 0.35
RARA P10276 1/20 0.33
RARB P10826 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6032726 0.84 RXRA (0.46) RXRAHNF4ARXRBRXRGRARG
SCHEMBL6561510 0.83 RXRA (0.39) RXRAHNF4ARXRBRXRGRARG
SCHEMBL6560970 0.81 RXRA (0.40) RXRAHNF4ARXRBRXRGRARG
SCHEMBL6561458 0.80 RXRA (0.40) RXRAHNF4ARARGRARARARB
SCHEMBL6559937 0.80 RXRA (0.45) RXRARXRBRXRGRARGRARA
SCHEMBL6033093 0.80 RXRA (0.37) RXRAHNF4ARXRBRXRGRARG
SCHEMBL6562412 0.79 RXRA (0.40) RXRAHNF4ARXRBRXRG
SCHEMBL6559816 0.78 RXRA (0.42) RXRAHNF4ARXRBRXRGRARG
SCHEMBL6032616 0.78 RXRA (0.47) RXRAHNF4ARXRBRXRGRARG
SCHEMBL6032618 0.78 RARA (0.41) RXRAHNF4ARXRBRXRGRARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1086080-B1 DIARYLSELENIDE COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS GALDERMA RES & DEV (FR) 2004-08-25 EP claimed