Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 15/20 | 0.40 |
| ▸ | HNF4A | P41235 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6562412 | 0.89 | RXRA (0.40) | RXRAHNF4APPARGNR1H3 | |
| SCHEMBL6560970 | 0.84 | RXRA (0.40) | RXRAHNF4APPARGNR1H3RARA | |
| SCHEMBL6559941 | 0.84 | RXRA (0.48) | RXRAHNF4APPARGNR1H3RARA | |
| SCHEMBL6561037 | 0.84 | RXRA (0.41) | RXRAHNF4APPARGNR1H3PPARA | |
| SCHEMBL6560253 | 0.80 | RXRA (0.37) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL6562290 | 0.78 | RXRA (0.48) | RXRAHNF4APPARGNR1H3RARA | |
| SCHEMBL6033253 | 0.78 | RARA (0.41) | RXRAHNF4APPARGNR1H3RARA | |
| SCHEMBL6559816 | 0.78 | RXRA (0.42) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL6559937 | 0.78 | RXRA (0.45) | RXRAPPARGNR1H3RARARARB | |
| SCHEMBL6033001 | 0.76 | RXRA (0.50) | RXRAHNF4APPARGNR1H3RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086080-B1 | DIARYLSELENIDE COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2004-08-25 | — | — | EP | claimed |