SCHEMBL6562412

SCHEMBL6562412

CCOC(=O)CCCOc1cc2c(cc1[Se]c1ccc(C(=O)O)c(CC)n1)C(C)(C)CCC2(C)C

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
RXRA P19793 18/20 0.40
HNF4A P41235 5/20 0.39
BRD4 O60885 1/20 0.36
PPARG P37231 2/20 0.35
NR1H3 Q13133 2/20 0.35
RXRB P28702 3/20 0.34
RXRG P48443 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6561458 0.89 RXRA (0.40) RXRAHNF4APPARGNR1H3
SCHEMBL6560970 0.87 RXRA (0.40) RXRAHNF4APPARGNR1H3RXRB
SCHEMBL6560072 0.85 RXRA (0.50) RXRAHNF4APPARGNR1H3RXRB
SCHEMBL6563043 0.83 RXRA (0.41) RXRAHNF4ABRD4PPARGNR1H3
SCHEMBL6559937 0.80 RXRA (0.45) RXRAPPARGNR1H3RXRBRXRG
SCHEMBL6032646 0.80 RARA (0.43) RXRAHNF4ABRD4PPARGNR1H3
SCHEMBL6560253 0.79 RXRA (0.37) RXRAHNF4ARXRBRXRG
SCHEMBL6559631 0.79 RXRA (0.51) RXRAHNF4APPARGNR1H3RXRB
SCHEMBL6559816 0.78 RXRA (0.42) RXRAHNF4ARXRBRXRG
SCHEMBL6032681 0.75 L3MBTL1 (0.43) RXRAHNF4ABRD4PPARGNR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1086080-B1 DIARYLSELENIDE COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS GALDERMA RES & DEV (FR) 2004-08-25 EP claimed