Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6562176 | 0.79 | ALDH1A1 (0.54) | HTR7ALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL7805593 | 0.76 | HTR7 (0.52) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL7944215 | 0.73 | HTR7 (0.70) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL14404 | 0.70 | HTR7 (0.38) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL7803876 | 0.70 | HTR7 (0.65) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL29904797 | 0.70 | HTR7 (1.00) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL6560573 | 0.68 | HTR7 (0.62) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL6561330 | 0.68 | HTR7 (0.51) | HTR7ALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL7949356 | 0.68 | HTR7 (0.65) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL6563153 | 0.67 | HTR7 (0.56) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071670-B1 | NOVEL DIPHENYL-SUBSTITUTED 5-RING-HETEROCYCLES, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-07-07 | — | — | EP | disclosed |
| US-6255327-B1 | ANTIHYPOXC, ANTIISCHEMIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-03 | — | — | US | disclosed |