Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HTR7 | P34969 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TNKS | O95271 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560795 | 0.79 | HTR7 (0.52) | ALDH1A1HTR7KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL7944253 | 0.76 | HTR7 (0.49) | ALDH1A1HTR7KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL6560069 | 0.74 | HTR7 (0.55) | ALDH1A1HTR7KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL7944215 | 0.70 | HTR7 (0.70) | ALDH1A1HTR7KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL7805547 | 0.69 | CA12 (0.54) | ALDH1A1GAAKDM4ESMN1; SMN2TNKS | |
| SCHEMBL7946819 | 0.69 | HTR7 (0.52) | ALDH1A1HTR7KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL7805578 | 0.68 | HTR7 (0.48) | ALDH1A1HTR7KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL29904797 | 0.67 | HTR7 (1.00) | ALDH1A1HTR7KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL15886588 | 0.67 | ALDH1A1 (0.49) | ALDH1A1GAAKDM4ESMN1; SMN2TNKS | |
| SCHEMBL6561335 | 0.67 | HTR7 (0.52) | ALDH1A1HTR7KDM4ESMN1; SMN2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071670-B1 | NOVEL DIPHENYL-SUBSTITUTED 5-RING-HETEROCYCLES, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-07-07 | — | — | EP | disclosed |
| US-6255327-B1 | ANTIHYPOXC, ANTIISCHEMIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-03 | — | — | US | disclosed |