Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.56 |
| ▸ | RNF4 | P78317 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 3/20 | 0.52 |
| ▸ | CNR1 | P21554 | 2/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5191196 | 0.94 | ACHE (0.54) | NR3C1RNF4ACHEMAPK1CNR2 | |
| SCHEMBL16494668 | 0.90 | RNF4 (0.53) | NR3C1RNF4ACHEMAPK1CNR2 | |
| SCHEMBL5810482 | 0.89 | ACHE (0.64) | NR3C1ACHECNR2CNR1ALDH1A1 | |
| SCHEMBL28700635 | 0.88 | PTPN1 (0.54) | NR3C1RNF4ACHEMAPK1CNR2 | |
| SCHEMBL5811431 | 0.86 | ACHE (0.53) | NR3C1ACHECNR2KEAP1NFE2L2 | |
| SCHEMBL340292 | 0.85 | KEAP1 (0.59) | KEAP1NFE2L2RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL7001778 | 0.85 | CYP2C19 (0.63) | NR3C1RNF4ACHEMAPK1CNR2 | |
| SCHEMBL10833174 | 0.84 | TSPO (0.57) | NR3C1KEAP1ALDH1A1LMNA | |
| SCHEMBL5189401 | 0.84 | TSHR (0.57) | NR3C1CNR2ALDH1A1LMNARAB9A | |
| SCHEMBL28565303 | 0.83 | CYP2C19 (0.71) | NR3C1CNR2CNR1KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644887-A1 | PROCESS FOR THE PREPARATION OF CLAVULANIC ACID. | SMITHKLINE BEECHAM PLC (GB) | 1995-03-29 | — | — | EP | claimed |
| WO-1993025557-A1 | PROCESS FOR THE PREPARATION OF CLAVULANIC ACID | SMITHKLINE BEECHAM PLC (GB) | 1993-12-23 | — | — | WO | claimed |
| EP-0804441-B1 | CLAVULANIC ACID EXTRACTION PROCESS | SMITHKLINE BEECHAM PLC (GB) | 2004-03-17 | — | — | EP | disclosed |
| US-6172221-B1 | AMINE SALT FORMATION | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-01-09 | — | — | US | disclosed |
| EP-0806426-A1 | Process for the preparation of clavulanic acid | SMITHKLINE BEECHAM PLC (GB) | 1997-11-12 | — | — | EP | disclosed |
| EP-0801069-A1 | Process for the preparation of clavulanic acid | SMITHKLINE BEECHAM PLC (GB) | 1997-10-15 | — | — | EP | disclosed |
| EP-0747383-A2 | Polyamine salts of clavulanic acid | SMITHKLINE BEECHAM PLC (GB) | 1996-12-11 | — | — | EP | disclosed |
| EP-0672669-A1 | Process for the preparation of clavulanic acid | SMITHKLINE BEECHAM PLC (GB) | 1995-09-20 | — | — | EP | disclosed |
| EP-0672670-A1 | Process for the preparation of clavulanic acid | SMITHKLINE BEECHAM PLC (GB) | 1995-09-20 | — | — | EP | disclosed |
| EP-0644887-A1 | PROCESS FOR THE PREPARATION OF CLAVULANIC ACID. | SMITHKLINE BEECHAM PLC (GB) | 1995-03-29 | — | — | EP | disclosed |
| WO-1993025557-A1 | PROCESS FOR THE PREPARATION OF CLAVULANIC ACID | SMITHKLINE BEECHAM PLC (GB) | 1993-12-23 | — | — | WO | disclosed |
| EP-0061765-B1 | BETA-LACTAMS | E.R. SQUIBB & SONS, INC. (US) | 1985-08-28 | — | — | EP | disclosed |
| US-4478749-A | AMINO ACID DERTIVATIVES ANTIBIOTICS | E. R. SQUIBB & SONS, INC. (US) | 1984-10-23 | — | — | US | disclosed |
| EP-0061765-A1 | Beta-Lactams | E.R. SQUIBB & SONS, INC. (US) | 1982-10-06 | — | — | EP | disclosed |