Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6562323 | 0.81 | CTSD (0.35) | CTSDCYP1A2CYP3A4CYP2C19PDGFRB | |
| SCHEMBL6562536 | 0.75 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL29177185 | 0.67 | CYP1A2 (0.35) | CTSDCYP1A2CYP3A4CYP2C19PDGFRB | |
| SCHEMBL29580615 | 0.66 | PDGFRB (0.51) | CYP1A2CYP3A4PDGFRBFGFR1PDGFRA | |
| SCHEMBL11597118 | 0.65 | CYP1A2 (0.73) | CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL3943281 | 0.65 | CYP1A2 (0.36) | CTSDCYP1A2CYP3A4CYP2C19PDGFRB | |
| SCHEMBL5557584 | 0.64 | PGR (0.41) | CTSDCYP1A2CYP3A4CYP2C19PDGFRB | |
| SCHEMBL25412108 | 0.64 | CYP1A2 (0.50) | CYP1A2RAB9AALDH1A1 | |
| SCHEMBL29764342 | 0.64 | CYP1A2 (0.50) | CTSDCYP1A2CYP3A4CYP2C19NPC1 | |
| SCHEMBL7594064 | 0.63 | ALDH1A1 (0.54) | CYP1A2CYP3A4CYP2C19NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1085009-B1 | INDAN DERIVATIVES | NISSAN CHEMICAL IND LTD (JP) | 2004-11-10 | — | — | EP | disclosed |
| US-6486178-B1 | Indane derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2002-11-26 | — | — | US | disclosed |
| EP-1085009-A1 | INDAN DERIVATIVES | Nissan Chemical Industries, Ltd. (JP) | 2001-03-21 | — | — | EP | disclosed |