Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TOP1 | P11387 | 2/20 | 0.44 |
| ▸ | GCGR | P47871 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11665495 | 0.95 | BACE1 (0.44) | PTGS2PTGS1MAPTBACE1GPR3 | |
| SCHEMBL13682561 | 0.89 | MEN1 (0.48) | PTGS2PTGS1MAPTTOP1GCGR | |
| SCHEMBL30997630 | 0.86 | MAPT (0.45) | PTGS2PTGS1MAPTBACE1GPR3 | |
| SCHEMBL27649740 | 0.85 | PTGS2 (0.57) | PTGS2PTGS1TOP1GCGRMAPK14 | |
| Hydrogen Sulfide SCHEMBL27719947 | 0.83 | PTGS2 (0.55) | PTGS2PTGS1TOP1GCGRMAPK14 | |
| SCHEMBL18241028 | 0.83 | PTGS2 (0.55) | PTGS2PTGS1TOP1GCGRMAPK14 | |
| SCHEMBL16673243 | 0.83 | MEN1 (0.49) | PTGS2PTGS1MAPTTOP1GCGR | |
| SCHEMBL18561607 | 0.80 | MEN1 (0.50) | PTGS2PTGS1MAPTADORA1ADORA2A | |
| SCHEMBL30388410 | 0.79 | MAPT (0.47) | MAPTADORA1ADORA2AMETAP2 | |
| SCHEMBL20777561 | 0.79 | MAPT (0.47) | MAPTADORA1ADORA2AMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122746-B1 | Composition for film formation and insulating film | JSR CORP (JP) | 2004-09-22 | — | — | EP | disclosed |
| US-6468589-B2 | A HEAT-CURED POLYETHER BASED ON A 9,9-BIS(P-HYDROXYPHENYL)-FLUORENE HAVING AT LEAST ONE ALKYL SUBSTITUENT AND A DIHYDROXY AROMATIC COMONOMER; LOW DIELECTRIC PROTECTIVE COATINGS; HEAT RESISTANCE; NONCRACKING | JSR CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| US-20010012870-A1 | Composition for film formation and insulating film | JSR CORPORATION (JP) | 2001-08-09 | — | — | US | disclosed |
| EP-1122746-A1 | Composition for film formation and insulating film | JSR Corporation (JP) | 2001-08-08 | — | — | EP | disclosed |