SCHEMBL30997630

SCHEMBL30997630

Fc1ccc(-c2ccccc2-c2ccccc2)c(-c2ccccc2-c2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.45
HTT P42858 2/20 0.45
GPR3 P46089 1/20 0.45
MEN1 O00255 1/20 0.45
APAF1 O14727 1/20 0.45
NPC1 O15118 1/20 0.45
LMNA P02545 1/20 0.45
THRB P10828 1/20 0.45
XBP1 P17861 1/20 0.45
PTBP1 P26599 1/20 0.45
RAB9A P51151 1/20 0.45
GALK1 P51570 1/20 0.45
BLM P54132 1/20 0.45
SMAD3 P84022 1/20 0.45
KMT2A Q03164 1/20 0.45
ATM Q13315 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
PTGS2 P35354 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11665495 0.91 BACE1 (0.44) MAPTGPR3PTGS2PTGS1BACE1
SCHEMBL9856229 0.88 GPR3 (0.54) MAPTHTTGPR3MEN1APAF1
SCHEMBL6561402 0.86 PTGS2 (0.46) MAPTGPR3PTGS2PTGS1BACE1
SCHEMBL4621728 0.84 ALDH1A1 (0.54) MAPTMEN1NPC1LMNAKMT2A
SCHEMBL27649740 0.80 PTGS2 (0.57) PTGS2PTGS1ALDH1A1HSD17B10CYP2A6
SCHEMBL6825024 0.80 BACE1 (0.52) MAPTHTTMEN1APAF1NPC1
SCHEMBL20777561 0.79 MAPT (0.47) MAPTHTTMEN1KMT2AL3MBTL1
SCHEMBL30388410 0.79 MAPT (0.47) MAPTHTTMEN1KMT2AL3MBTL1
SCHEMBL4620558 0.79 JAK2 (0.52) MEN1NPC1LMNARAB9AKMT2A
SCHEMBL9228338 0.79 GRM2 (0.42) MAPTHTTMEN1LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240251665-A1 TRANSVERSE CURRENT SUPPRESSING MATERIAL, CARBAZOLE COMPOUND, HOLE-INJECTION LAYER AND ORGANIC ELECTROLUMINESCENT ELEMENT TOSOH CORPORATION (JP) 2024-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240251665-A1 TRANSVERSE CURRENT SUPPRESSING MATERIAL, CARBAZOLE COMPOUND, HOLE-INJECTION LAYER AND ORGANIC ELECTROLUMINESCENT ELEMENT AXIN2, FZD7, SLC39A3 MAPT 3209/4885HTT 337/4885GPR3 3278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.