SCHEMBL11665495

SCHEMBL11665495

Fc1ccc(-c2ccccc2)c(-c2ccccc2)c1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.44
GPR3 P46089 1/20 0.43
ALOX5 P09917 1/20 0.43
METAP2 P50579 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP2A6 P11509 1/20 0.42
MAPT P10636 3/20 0.41
MAP2K4 P45985 1/20 0.41
AR P10275 1/20 0.41
PTGS2 P35354 2/20 0.39
PTGS1 P23219 1/20 0.39
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6561402 0.95 PTGS2 (0.46) BACE1GPR3METAP2MAPTPTGS2
SCHEMBL30997630 0.91 MAPT (0.45) BACE1GPR3ALOX5METAP2CYP1A2
SCHEMBL13682561 0.84 MEN1 (0.48) MAPTPTGS2PTGS1
SCHEMBL20777561 0.83 MAPT (0.47) METAP2MAPTAR
SCHEMBL30388410 0.83 MAPT (0.47) METAP2MAPTAR
SCHEMBL30216000 0.83 MEN1 (0.49) BACE1CYP1A2MAPTPTGS2PTGS1
SCHEMBL412228 0.83 MEN1 (0.49) BACE1CYP1A2MAPTPTGS2PTGS1
SCHEMBL20777582 0.82 MAPT (0.46) METAP2MAPTAR
SCHEMBL14832985 0.81 ALOX5 (0.61) BACE1GPR3ALOX5MAPT
SCHEMBL3756100 0.79 ESR2 (0.59) BACE1GPR3ALOX5CYP2A6PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-53082679-A None JP disclosed
EP-2108690-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-10-14 EP disclosed
JP-S5382679-A LIQUID CRYSTAL COMPOSITION SEIKO EPSON CORP 1978-07-21 JP disclosed