SCHEMBL1367532

SCHEMBL1367532

Cc1ccc(N(C)C)c(C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.44
TP53 P04637 2/20 0.44
CYP3A4 P08684 2/20 0.42
ADRA2A P08913 1/20 0.42
ALDH1A1 P00352 2/20 0.42
TSHR P16473 1/20 0.42
ESR1 P03372 1/20 0.42
CYP1A2 P05177 2/20 0.39
CYP2A6 P11509 2/20 0.39
PYCR1 P32322 1/20 0.37
RAPGEF4 Q8WZA2 2/20 0.37
KDM4E B2RXH2 1/20 0.36
HIF1A Q16665 1/20 0.36
EPAS1 Q99814 1/20 0.36
GAA P10253 1/20 0.35
KMT2A Q03164 1/20 0.35
ACHE P22303 2/20 0.35
THRB P10828 1/20 0.35
ALOX15 P16050 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lithium Ion SCHEMBL19732658 0.97 TDP1 (0.42) TDP1TP53CYP3A4ADRA2AALDH1A1
Hydrochloric Acid SCHEMBL2855745 0.97 TDP1 (0.42) TDP1TP53CYP3A4ADRA2AALDH1A1
SCHEMBL5436534 0.84 TDP1 (0.44) TDP1TP53CYP3A4ADRA2AALDH1A1
SCHEMBL18645177 0.81 ALDH1A1 (0.41) TDP1CYP3A4ALDH1A1TSHRESR1
SCHEMBL585557 0.81 TDP1 (0.46) TDP1TP53CYP3A4ADRA2AALDH1A1
SCHEMBL5641724 0.81 ALDH1A1 (0.43) TDP1TP53CYP3A4ADRA2AALDH1A1
SCHEMBL30573468 0.81 TDP1 (0.46) TDP1TP53CYP3A4ADRA2AALDH1A1
SCHEMBL19121570 0.80 TDP1 (0.41) TDP1TP53CYP3A4ADRA2AALDH1A1
SCHEMBL21646868 0.80 TDP1 (0.41) TDP1TP53CYP3A4ADRA2AALDH1A1
SCHEMBL4804383 0.80 ALDH1A1 (0.41) TDP1TP53CYP3A4ADRA2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6664357-B1 Forming homogeneous mixture of polymerizable (meth)acrylate monomers and oligomers, chelating agent, organic cyclic sulfimide accelerator, heating, adding tertiary amine accelerator, adding photoinitiator at room temperature NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION 2003-12-16 US claimed
US-4588583-A ACRYLATES, ESTERS, BONE CEMENT BEIERSDORF AKTIENGESELLSCHAFT (DE) 1986-05-13 US claimed
US-4235986-A ACRYLATE ESTER MONOMER NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1980-11-25 US claimed
EP-4029839-B1 GLASS POWDER AND CHEMICAL POLYMERIZATION INITIATOR G C DENTAL IND CORP (JP) 2026-05-06 EP disclosed
US-12600867-B2 Method of coating article, use for coating article, and polymerizable composition GC CORPORATION (JP) 2026-04-14 US disclosed
US-12569409-B2 Dental polymerizable composition GC CORPORATION (JP) 2026-03-10 US disclosed
US-12478561-B2 Dental composition and dental restorative kit GC CORPORATION (JP) 2025-11-25 US disclosed
US-12460021-B2 Glass powder and chemical polymerization initiator GC CORPORATION (JP) 2025-11-04 US disclosed
US-20250223219-A1 GLASS COMPOSITION GC CORPORATION (JP) 2025-07-10 US disclosed
US-20250213435-A1 DENTAL ADHESIVE COMPOSITION GC CORPORATION (JP) 2025-07-03 US disclosed
US-20250213436-A1 POLYMERIZATION ACCELERATOR, POLYMERIZATION INITIATOR, CURABLE COMPOSITION PREPARATION KIT, CURABLE COMPOSITION, CURED PRODUCT, AND DENTAL MATERIAL MITSUI CHEMICALS, INC. (JP) 2025-07-03 US disclosed
US-4605766-A REACTING AROMATIC AMINES WITH ETHERS IN PRESENCE OF CATALYST CONTAINING IRON OXIDE ETHYL CORPORATION (US) 1986-08-12 US disclosed
US-4599449-A POSSIBLE RECOVERY OF UNUSED ALCOHOL ETHYL CORPORATION (US) 1986-07-08 US disclosed
US-4588583-A ACRYLATES, ESTERS, BONE CEMENT BEIERSDORF AKTIENGESELLSCHAFT (DE) 1986-05-13 US disclosed
EP-0164049-A2 Process for preparing HMG-CoA reductase inhibtors with a 3,5-dihydroxypentanoate subunit MERCK & CO. INC. (US) 1985-12-11 EP disclosed
EP-0148009-A2 Process for the alkylation of aromatic amines and use of the products thereof ETHYL CORPORATION (US) 1985-07-10 EP disclosed
EP-0111759-A2 Surgical material Beiersdorf Aktiengesellschaft (DE) 1984-06-27 EP disclosed
EP-0073277-A1 Process for producing orthoalkylated aromatic amines MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1983-03-09 EP disclosed
US-4351958-A Process for producing orthoalkylated aromatic amine MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1982-09-28 US disclosed
US-4315068-A CONTAINING A COBALT-AMMINE COMPLEX AND A DIOXIME OR A BISIMIDAZOLIN-3-ONE CHELATING AGENT; STABILITY; COLOR DILMS RICOH CO., LTD. (JP) 1982-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569409-B2 Dental polymerizable composition VCL, ACR, TPO TDP1 123/4885TP53 1410/4885CYP3A4 4382/4885
US-12600867-B2 Method of coating article, use for coating article, and polymerizable composition SARS1, SPIN1, ESPL1 TDP1 2182/4885TP53 2176/4885CYP3A4 2106/4885
US-20250213436-A1 POLYMERIZATION ACCELERATOR, POLYMERIZATION INITIATOR, CURABLE COMPOSITION PREPARATION KIT, CURABLE COMPOSITION, CURED PRODUCT, AND DENTAL MATERIAL DNMT3L, CDK9, CDK6 TDP1 610/4885TP53 3257/4885CYP3A4 4408/4885
US-20250213435-A1 DENTAL ADHESIVE COMPOSITION ITGA1, ITGA2, ITGB6 TDP1 3848/4885TP53 4316/4885CYP3A4 2493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.