Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.42 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563814 | 0.86 | PLAU (0.54) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL6565051 | 0.83 | F10 (0.50) | PRSS1F2HDAC1HDAC8HDAC6 | |
| SCHEMBL6561959 | 0.80 | MLYCD (0.41) | MLYCDPRSS1F2NAMPTF10 | |
| SCHEMBL7668378 | 0.77 | PLAU (0.49) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL6563498 | 0.73 | PRSS1 (0.44) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL6563422 | 0.72 | PRSS1 (0.42) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL7674335 | 0.71 | PRSS1 (0.49) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL6561871 | 0.70 | KMT2A (0.46) | HDAC1HDAC6NAMPTF10 | |
| SCHEMBL6563528 | 0.70 | PRSS1 (0.51) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL10412444 | 0.69 | ALOX5 (0.49) | MLYCDHDAC1HDAC8HDAC6NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |