Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 8/20 | 0.44 |
| ▸ | F2 | P00734 | 4/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.43 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565505 | 0.80 | MTOR (0.36) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL7674335 | 0.79 | PRSS1 (0.49) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL6561828 | 0.73 | MLYCD (0.44) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL6563626 | 0.72 | F2 (0.43) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL20001656 | 0.70 | PRSS1 (0.66) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL7668378 | 0.69 | PLAU (0.49) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL6563814 | 0.68 | PLAU (0.54) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL6563528 | 0.68 | PRSS1 (0.51) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL5885652 | 0.67 | PRSS1 (0.45) | PRSS1F2PRSS2PRSS3BCL2L1 | |
| SCHEMBL6563934 | 0.67 | SRD5A2 (0.49) | BCL2L1MCL1LMNASCN9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |