Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565512 | 0.89 | GAA (0.40) | GAAHPGDNAMPTALDH1A1CA12 | |
| SCHEMBL6563029 | 0.88 | ALDH1A1 (0.51) | ALDH1A1CA2F2F11 | |
| SCHEMBL6565962 | 0.88 | SPHK2 (0.41) | NAMPTHSD11B1F2PREPDPP4 | |
| SCHEMBL6563770 | 0.86 | SPHK1 (0.43) | ALDH1A1F2F11 | |
| SCHEMBL6563261 | 0.86 | HSD11B1 (0.38) | GAAHPGDNAMPTALDH1A1CA12 | |
| SCHEMBL6565356 | 0.85 | GAA (0.42) | GAAHPGDNAMPTALDH1A1CA12 | |
| SCHEMBL6565248 | 0.83 | GRM5 (0.56) | HPGDALDH1A1CA12CA1CA2 | |
| SCHEMBL6563266 | 0.83 | LRRK2 (0.42) | GAAHPGDNAMPTALDH1A1CA12 | |
| SCHEMBL6563410 | 0.83 | GAA (0.40) | GAAHPGDNAMPTALDH1A1CA12 | |
| SCHEMBL6563675 | 0.83 | F10 (0.47) | HPGDALDH1A1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |