Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 11/20 | 0.41 |
| ▸ | RARA | P10276 | 3/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | MPL | P40238 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6547940 | 0.89 | HCRTR1 (0.39) | RARBRARAFOLH1HCRTR1HCRTR2 | |
| SCHEMBL6564029 | 0.88 | NPC1 (0.41) | RARBRARAFOLH1MPLNPC1 | |
| SCHEMBL6937388 | 0.82 | PTPN11 (0.52) | RARBRARATP53PTPN11 | |
| SCHEMBL7604365 | 0.80 | PTPN11 (0.42) | RARBRARARARGNPC1TP53 | |
| SCHEMBL6562349 | 0.79 | MAPT (0.42) | RARBRARARARGNPC1RAB9A | |
| SCHEMBL6547284 | 0.78 | MAPT (0.44) | RARBFOLH1HCRTR1HCRTR2PTPN11 | |
| SCHEMBL7526394 | 0.77 | PDCD1 (0.38) | RARBNPC1SMN1; SMN2HCRTR1HCRTR2 | |
| SCHEMBL9626753 | 0.76 | PTPN11 (0.58) | RARBRARATP53PTPN11 | |
| SCHEMBL6547277 | 0.76 | MAPT (0.42) | RARBFOLH1HCRTR1HCRTR2PTPN11 | |
| SCHEMBL8015669 | 0.76 | RARB (0.54) | RARBRARARARGFOLH1MPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1225212-B1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL CO (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-6677475-B2 | FOR USE IN LIQUID CRYSTAL DISPLAY DEVICE | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 2004-01-13 | — | — | US | disclosed |
| EP-1225212-A1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2002-07-24 | — | — | EP | disclosed |