SCHEMBL6562998

SCHEMBL6562998

CCC1(c2ccc(CCc3ccc(CO)c(CO)c3)s2)OCCO1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
VDR P11473 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6564475 0.84 VDR (0.33) VDR
SCHEMBL6564918 0.80 VDR (0.31) VDR
SCHEMBL3280780 0.79 VDR (0.39) VDR
SCHEMBL7613672 0.72 VDR (0.34) VDR
SCHEMBL6564204 0.70 POLB (0.49) VDR
SCHEMBL6562789 0.67 PRMT6 (0.33)
SCHEMBL13953779 0.66 CNR1 (0.50) VDR
SCHEMBL27589714 0.64
SCHEMBL18199330 0.63 TYR (0.48) VDR
SCHEMBL27489196 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1235824-B1 VITAMIN D ANALOGUES GALDERMA RES & DEV (FR) 2004-05-19 EP disclosed
US-6706725-B1 BIAROMATIC COMPOUNDS WHICH ARE VITAMIN D ANALOGUES GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2004-03-16 US disclosed
EP-1235824-A1 VITAMIN D ANALOGUES Galderma Research & Development, S.N.C. (FR) 2002-09-04 EP disclosed
WO-2001038320-A1 VITAMIN D ANALOGUES GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2001-05-31 WO disclosed