SCHEMBL3280780

SCHEMBL3280780

CCC1(c2cccc(CCc3ccc(CO)c(CO)c3)c2)OCCO1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
VDR P11473 2/20 0.39
CALM1 P0DP23 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27513285 0.87 CALM1 (0.39) CALM1
SCHEMBL6562998 0.79 VDR (0.33) VDR
SCHEMBL6564475 0.78 VDR (0.33) VDR
SCHEMBL3283097 0.78 KAT8 (0.39)
SCHEMBL28875142 0.75 L3MBTL1 (0.36)
SCHEMBL3280588 0.75 CYP4F2 (0.38)
SCHEMBL6756665 0.73 VDR (0.47) VDR
SCHEMBL7770806 0.71 VDR (0.36) VDR
SCHEMBL13593734 0.70 CHRNA1 (0.41)
SCHEMBL6157330 0.69 VDR (0.50) VDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7700657-B2 Vitamin D analogs GALDERMA RESEARCH & DEVELOPMENT (FR) 2010-04-20 US disclosed
EP-1395538-B1 VITAMIN D ANALOGUES GALDERMA RES & DEV (FR) 2009-12-30 EP disclosed
CN-1267394-C Vitamin D analogues GALDERMA RES & DEV (FR) 2006-08-02 CN disclosed
CN-1549803-A Vitamin D analogues �������о�����չ˽�����޹�˾ 2004-11-24 CN disclosed
US-20040224929-A1 Novel vitamin D analogs GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2004-11-11 US disclosed
EP-1395538-A1 VITAMIN D ANALOGUES Galderma Research & Development, S.N.C. (FR) 2004-03-10 EP disclosed
WO-2002094754-A1 VITAMIN D ANALOGUES GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2002-11-28 WO disclosed