Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985892 | 0.86 | L3MBTL1 (0.59) | L3MBTL1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL1075209 | 0.86 | L3MBTL1 (0.66) | L3MBTL1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL6563111 | 0.85 | L3MBTL1 (0.57) | L3MBTL1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL6563006 | 0.84 | L3MBTL1 (0.56) | L3MBTL1NPC1RAB9AKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL6564537 | 0.84 | L3MBTL1 (0.56) | L3MBTL1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL6565112 | 0.84 | L3MBTL1 (0.59) | L3MBTL1KMT2ATSHRFFAR4DAO | |
| Hydrochloric Acid SCHEMBL31346661 | 0.83 | L3MBTL1 (0.62) | L3MBTL1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL25488452 | 0.82 | L3MBTL1 (0.60) | L3MBTL1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL10066488 | 0.81 | L3MBTL1 (0.72) | L3MBTL1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL1300632 | 0.80 | L3MBTL1 (0.70) | L3MBTL1NPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040220411-A1 | Oxalic acid derivatives | MERCK PATENT GMBH (DE) | 2004-11-04 | — | — | US | disclosed |
| EP-1377543-A1 | OXALIC ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002083630-A1 | OXALIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220411-A1 | Oxalic acid derivatives | F11, F2, F12 | L3MBTL1 2292/4885NPC1 4104/4885RAB9A 2271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.