Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563104 | 0.86 | L3MBTL1 (0.62) | L3MBTL1MAPTALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL27612413 | 0.84 | L3MBTL1 (0.62) | L3MBTL1MAPTALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL1075209 | 0.83 | L3MBTL1 (0.66) | L3MBTL1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL6565112 | 0.82 | L3MBTL1 (0.59) | L3MBTL1MAPTKMT2ATSHRPOLB | |
| Hydrochloric Acid SCHEMBL31346661 | 0.81 | L3MBTL1 (0.62) | L3MBTL1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL25488452 | 0.80 | L3MBTL1 (0.60) | L3MBTL1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL10066488 | 0.79 | L3MBTL1 (0.72) | L3MBTL1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6563111 | 0.78 | L3MBTL1 (0.57) | L3MBTL1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL1301049 | 0.77 | L3MBTL1 (0.70) | L3MBTL1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL1300632 | 0.77 | L3MBTL1 (0.70) | L3MBTL1MAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030187037-A1 | Acetamide derivatives and the use thereof as inhibitors of coagulation factors xa and viia | MERCK-PATENT GMBH (DE) | 2003-10-02 | — | — | US | disclosed |
| US-20030171579-A1 | Urethane derivatives | MERCK PATENT GMBH (DE) | 2003-09-11 | — | — | US | disclosed |
| EP-1309573-A1 | URETHANE DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-05-14 | — | — | EP | disclosed |
| EP-1309549-A1 | ACETAMIDE DERIVATIVES AND THE USE THEREOF AS INHIBITORS OF COAGULATION FACTORS XA AND VIIA | MERCK PATENT GmbH (DE) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002010127-A1 | ACETAMIDE DERIVATIVES AND THE USE THEREOF AS INHIBITORS OF COAGULATION FACTORS XA AND VIIA | MERCK PATENT GMBH (DE) | 2002-02-07 | — | — | WO | disclosed |
| WO-2002010145-A1 | URETHANE DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187037-A1 | Acetamide derivatives and the use thereof as inhibitors of coagulation factors xa and viia | F12, F11, PLAT | L3MBTL1 2304/4885MAPT 4659/4885ALDH1A1 871/4885 |
| US-20030171579-A1 | Urethane derivatives | UTS2R, PLAUR, IL1A | L3MBTL1 3573/4885MAPT 4210/4885ALDH1A1 479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.