SCHEMBL6565112

SCHEMBL6565112

Cc1nc(-c2cccc(CNC(=O)O)c2)no1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.59
TSHR P16473 1/20 0.55
KMT2A Q03164 1/20 0.55
HPGDS O60760 3/20 0.53
CTSD P07339 2/20 0.52
FFAR4 Q5NUL3 1/20 0.49
DAO P14920 1/20 0.49
TP53 P04637 2/20 0.48
MAPT P10636 2/20 0.47
POLB P06746 1/20 0.47
AURKA O14965 1/20 0.47
AURKB Q96GD4 1/20 0.47
PLK1 P53350 1/20 0.47
MET P08581 1/20 0.47
ADORA2A P29274 1/20 0.47
ADORA1 P30542 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17335718 0.89 TSHR (0.57) L3MBTL1TSHRKMT2AHPGDSCTSD
SCHEMBL6565513 0.88 CTSD (0.54) L3MBTL1TSHRKMT2AHPGDSCTSD
SCHEMBL12747582 0.84 L3MBTL1 (0.62) L3MBTL1TSHRKMT2ACTSDFFAR4
SCHEMBL6563104 0.84 L3MBTL1 (0.62) L3MBTL1TSHRKMT2AHPGDSCTSD
Hydrochloric Acid SCHEMBL31346661 0.84 L3MBTL1 (0.62) L3MBTL1TSHRKMT2AHPGDSCTSD
SCHEMBL1075209 0.83 L3MBTL1 (0.66) L3MBTL1TSHRKMT2ADAOPLK1
SCHEMBL21683299 0.83 PLK1 (0.58) TSHRKMT2AMAPTPOLBPLK1
SCHEMBL7116372 0.82 L3MBTL1 (0.59) L3MBTL1TSHRKMT2AFFAR4DAO
SCHEMBL6985892 0.82 L3MBTL1 (0.59) L3MBTL1TSHRKMT2ACTSDDAO
SCHEMBL12747584 0.81 L3MBTL1 (0.57) L3MBTL1CTSDFFAR4DAOTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107982266-B Carbamate compounds and methods of making and using the same H.隆德贝克有限公司 2021-07-30 CN disclosed
US-20040220411-A1 Oxalic acid derivatives MERCK PATENT GMBH (DE) 2004-11-04 US disclosed
EP-1377543-A1 OXALIC ACID DERIVATIVES MERCK PATENT GmbH (DE) 2004-01-07 EP disclosed
WO-2002083630-A1 OXALIC ACID DERIVATIVES MERCK PATENT GMBH (DE) 2002-10-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040220411-A1 Oxalic acid derivatives F11, F2, F12 L3MBTL1 2292/4885TSHR 2897/4885KMT2A 3745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.