Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.45 |
| ▸ | ITGAV | P06756 | 1/20 | 0.45 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 6/20 | 0.41 |
| ▸ | CTSK | P43235 | 5/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560946 | 0.87 | MAPT (0.49) | MAPTTDP1KDM4EITGB1ITGB3 | |
| SCHEMBL6561292 | 0.81 | ITGB1 (0.56) | ITGB1ITGB3ITGA2BITGAVITGB5 | |
| SCHEMBL14799578 | 0.81 | ITGB1 (0.56) | ITGB1ITGB3ITGA2BITGAVITGB5 | |
| SCHEMBL6642502 | 0.81 | GAA (0.48) | MAPTITGB1ITGB3ITGA2BITGAV | |
| SCHEMBL27278646 | 0.80 | KLK5 (0.54) | MAPTTDP1KDM4EITGB1ITGB3 | |
| Hydrochloric Acid SCHEMBL6560412 | 0.79 | PTGS2 (0.41) | ITGB1KLKB1KLK1ITGA4 | |
| SCHEMBL20715930 | 0.79 | ITGB3 (0.61) | MAPTTDP1KDM4EITGB1ITGB3 | |
| SCHEMBL15140552 | 0.79 | ITGB1 (0.48) | MAPTTDP1KDM4EITGB1ITGB3 | |
| SCHEMBL15140555 | 0.79 | ITGB1 (0.48) | MAPTTDP1KDM4EITGB1ITGB3 | |
| SCHEMBL20865337 | 0.79 | KLK5 (0.53) | MAPTTDP1KDM4EITGB1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144365-B1 | INHIBITORS OF ALPHA-4 BETA-1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2004-03-17 | — | — | EP | disclosed |