Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | F7 | P08709 | 4/20 | 0.34 |
| ▸ | F2 | P00734 | 11/20 | 0.32 |
| ▸ | IDH1 | O75874 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 8/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.30 |
| ▸ | KLK1 | P06870 | 1/20 | 0.30 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | F3 | P13726 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
| ▸ | PLG | P00747 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565445 | 0.95 | ITGB3 (0.36) | ITGB3ITGA2BF7F2NPC1 | |
| SCHEMBL6563746 | 0.91 | F7 (0.37) | ITGB3ITGA2BF7F2NPC1 | |
| SCHEMBL7670894 | 0.91 | ITGB3 (0.39) | ITGB3ITGA2BF7F2F10 | |
| SCHEMBL6565368 | 0.90 | ITGB3 (0.37) | ITGB3ITGA2BF7F2IDH1 | |
| SCHEMBL6563523 | 0.88 | ITGB3 (0.37) | ITGB3ITGA2BF7F2RAB9A | |
| SCHEMBL6565399 | 0.85 | ITGB3 (0.37) | ITGB3ITGA2BF7F2F10 | |
| SCHEMBL6563598 | 0.84 | F7 (0.38) | ITGB3ITGA2BF7F2NPC1 | |
| SCHEMBL6563366 | 0.84 | ITGB3 (0.39) | ITGB3ITGA2BF7F2ALDH1A1 | |
| SCHEMBL6563089 | 0.84 | PLAU (0.33) | ITGB3ITGA2BF7F2F10 | |
| SCHEMBL6561894 | 0.84 | ITGB3 (0.40) | ITGB3ITGA2BF7F2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |