Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 7/20 | 0.38 |
| ▸ | F2 | P00734 | 5/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563746 | 0.94 | F7 (0.37) | F7F2ITGB3ITGA2BNPC1 | |
| SCHEMBL6565306 | 0.90 | F7 (0.39) | F7F2ITGB3ITGA2BAR | |
| SCHEMBL6565445 | 0.90 | ITGB3 (0.36) | F7F2ITGB3ITGA2BNPC1 | |
| SCHEMBL6563559 | 0.84 | ITGB3 (0.36) | F7F2ITGB3ITGA2BNPC1 | |
| SCHEMBL4250062 | 0.83 | ITGB3 (0.36) | F7F2ITGB3ITGA2BPLAU | |
| SCHEMBL7674138 | 0.82 | PLAU (0.34) | F7F2ITGB3ITGA2BPLAU | |
| SCHEMBL6565998 | 0.81 | ITGB3 (0.37) | F7F2ITGB3ITGA2BPLAU | |
| SCHEMBL7678059 | 0.81 | F7 (0.35) | F7F2ITGB3ITGA2BPLAU | |
| SCHEMBL6565368 | 0.80 | ITGB3 (0.37) | F7F2ITGB3ITGA2BHTT | |
| SCHEMBL6565929 | 0.79 | F7 (0.39) | F7F2ITGB3ITGA2BPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |