Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 6/20 | 0.38 |
| ▸ | UBE2M | P61081 | 2/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 3/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563598 | 0.90 | F7 (0.38) | F7ARF2ITGB3ITGA2B | |
| SCHEMBL6565368 | 0.89 | ITGB3 (0.37) | F7ARUBE2MDCUN1D1F2 | |
| SCHEMBL6563746 | 0.88 | F7 (0.37) | F7ARF2ITGB3ITGA2B | |
| SCHEMBL6565998 | 0.88 | ITGB3 (0.37) | F7F2ITGB3ITGA2B | |
| SCHEMBL4250062 | 0.81 | ITGB3 (0.36) | F7F2ITGB3ITGA2B | |
| SCHEMBL7674138 | 0.80 | PLAU (0.34) | F7F2ITGB3ITGA2B | |
| SCHEMBL6565445 | 0.80 | ITGB3 (0.36) | F7F2ITGB3ITGA2B | |
| SCHEMBL6565297 | 0.80 | F7 (0.38) | F7ARF2ITGB3ITGA2B | |
| SCHEMBL6563559 | 0.79 | ITGB3 (0.36) | F7F2ITGB3ITGA2B | |
| SCHEMBL7678059 | 0.79 | F7 (0.35) | F7F2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |