Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565301 | 0.90 | CA12 (0.31) | CA12CA1CA2CA9 | |
| SCHEMBL6563913 | 0.82 | CA12 (0.33) | CA12CA1CA2CA9 | |
| SCHEMBL6561879 | 0.77 | PTPN11 (0.38) | PTPN11 | |
| SCHEMBL6565533 | 0.76 | ACACB (0.45) | PTPN11 | |
| SCHEMBL6563526 | 0.75 | PTPN11 (0.38) | PTPN11 | |
| SCHEMBL6561973 | 0.74 | JAK1 (0.38) | PTPN11 | |
| SCHEMBL6565215 | 0.73 | PIK3CA (0.38) | PTPN11 | |
| SCHEMBL6563355 | 0.72 | PTPN11 (0.47) | PTPN11CA12CA1CA2 | |
| SCHEMBL6563070 | 0.72 | PTPN11 (0.44) | PTPN11 | |
| SCHEMBL6565417 | 0.72 | PTPN11 (0.36) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |