Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.33 |
| ▸ | F2 | P00734 | 3/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.32 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.32 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.32 |
| ▸ | F7 | P08709 | 2/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | KLK1 | P06870 | 1/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | F3 | P13726 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564407 | 0.88 | CA12 (0.34) | CA12CA1CA2CA9PRSS1 | |
| SCHEMBL6563695 | 0.82 | PTPN11 (0.34) | CA12CA1CA2CA9 | |
| SCHEMBL6771187 | 0.79 | MAPT (0.38) | CA12CA1CA2CA9PRSS1 | |
| SCHEMBL6563544 | 0.76 | RXRA (0.38) | PRSS1F2PRSS2PRSS3F10 | |
| SCHEMBL6563546 | 0.75 | F10 (0.38) | F2F7F10F3ITGB3 | |
| SCHEMBL6562124 | 0.75 | KLK5 (0.47) | PRSS1F2KLK1KLK5 | |
| SCHEMBL6565301 | 0.71 | CA12 (0.31) | CA12CA1CA2CA9 | |
| SCHEMBL7675036 | 0.71 | F10 (0.42) | CA1CA2PRSS1F2PRSS2 | |
| SCHEMBL6563461 | 0.71 | PRSS1 (0.49) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL6565349 | 0.70 | F2 (0.38) | PRSS1F2PRSS2PRSS3TMPRSS6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |