Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 5/20 | 0.44 |
| ▸ | PPARG | P37231 | 5/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 4/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565434 | 0.85 | PTPN11 (0.41) | PTPN11PPARAPPARGPTGESPPARD | |
| SCHEMBL6563283 | 0.84 | PTPN11 (0.46) | PTPN11PTGESCYP17A1 | |
| SCHEMBL6563070 | 0.82 | PTPN11 (0.44) | PTPN11PPARAPPARGPPARDCYP17A1 | |
| SCHEMBL7686729 | 0.80 | PTPN11 (0.43) | PTPN11LMNA | |
| SCHEMBL7674981 | 0.80 | ABL1 (0.43) | PTPN11LMNA | |
| SCHEMBL6563676 | 0.80 | NAMPT (0.42) | PTPN11PPARAPPARGPPARDCYP17A1 | |
| SCHEMBL6561813 | 0.80 | PTPN11 (0.42) | PTPN11PTGES | |
| SCHEMBL6565384 | 0.79 | GRM5 (0.46) | PTPN11 | |
| SCHEMBL6565322 | 0.79 | RAB9A (0.46) | CTSKCTSLCTSBLMNA | |
| SCHEMBL6563536 | 0.78 | PPARG (0.39) | PTPN11PPARAPPARGPTGESPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |