Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.35 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL211836 | 0.94 | TSHR (0.39) | GABRR1GABRR2BLMGABRR3LMNA | |
| Ammonia Solution, Strong SCHEMBL3280212 | 0.92 | TSHR (0.38) | GABRR1GABRR2BLMGABRR3LMNA | |
| Maleic Acid SCHEMBL4981536 | 0.92 | TSHR (0.38) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL6061868 | 0.92 | TSHR (0.38) | GABRR1GABRR2BLMGABRR3LMNA | |
| Methacrylic Acid SCHEMBL4684697 | 0.91 | GABRR1 (0.32) | GABRR1GABRR2BLMGABRR3LMNA | |
| Acrylic Acid SCHEMBL6444076 | 0.90 | LMNA (0.40) | GABRR1GABRR2BLMGABRR3LMNA | |
| Vinyl Chloride SCHEMBL6562575 | 0.89 | GABRR1 (0.35) | GABRR1GABRR2BLMGABRR3LMNA | |
| Vinyl Chloride SCHEMBL259499 | 0.89 | GABRR1 (0.35) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL7852607 | 0.85 | ALDH1A1 (0.46) | TSHRHCAR2 | |
| Acrylic Acid SCHEMBL6562656 | 0.85 | LMNA (0.36) | GABRR1GABRR2BLMGABRR3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1193898-C | Ink jet recording medium | CANON KK (JP) | 2005-03-23 | — | — | CN | disclosed |
| US-6730375-B2 | POROUS RESIN LAYER CONTAINING WATER-DISPERSIBLE RESIN PARTICLES TYPE A AND B, WHERE PARTICLES A HAVE HIGHER FILM FORMING TEMPERATURE AND LARGER PARTICLE SIZE THAN A; INK ABSORBENCY, ABRASION RESISTANCE | CANON KABUSHIKI KAISHA (JP) | 2004-05-04 | — | — | US | disclosed |
| EP-1219458-B1 | Ink-jet recording medium | CANON KK (JP) | 2004-03-17 | — | — | EP | disclosed |
| US-20020136868-A1 | Ink-Jet recording medium | CANON KABUSHIKI KAISHA (JP) | 2002-09-26 | — | — | US | disclosed |
| CN-1362333-A | Ink jet recording medium | CANON KK (JP) | 2002-08-07 | — | — | CN | disclosed |
| EP-1219458-A2 | Ink-jet recording medium | CANON KABUSHIKI KAISHA (JP) | 2002-07-03 | — | — | EP | disclosed |